Hampton University
School of Engineering and Technology, Department of chemical Engineering

Raymond E. Samuel, M.D., Ph.D

Assistant Dean, School of Engineering & Technology

Associate Professor, Department of Chemical Engineering

Telephone: (757) 727-5299
E-mail: raymond.samuel@hamptonu.edu

Dr. Samuel received a B.S. in Chemical Engineering in 1984 at the Massachusetts Institute of Technology. He was introduced to biochemical engineering during summer internships at E.I. DuPont and De Nemoir Company in Glascow, Delaware, where he worked on the optimization of a beta-glucosidase fermentation process. He then spent the subsequent three years performing biochemical engineering research in the laboratory of Professor Charles Cooney, as part of MIT’s Undergraduate Research Opportunity Program (UROP). He then obtained the combined M.D.-Ph.D. degrees through participation in the NIH-sponsored Medical Scientist Training Program at the Albert Einstein Medical School of Yeshiva University. He subsequently completed clinical training in Orthopaedic Surgery at the Montefiore Medical Center (Bronx, New York).

Dr. Samuel performed post-doctoral training in the Department of Surgery at the Massachusetts General Hospital, the Department of Cell Biology at Harvard Medical School, and the Department of Orthopaedic Surgery at the Children’s Hospital-Boston. He was an instructor in the Department of Orthopaedic Surgery at the Children’s Hospital-Boston for several years prior to his return to the Department of Chemical Engineering at the Massachusetts Institute of Technology. Dr. Samuel’s research activities include non-viral gene transfer drug delivery systems, musculoskeletal tissue engineering, thin film surface functionalization of biomaterials, and role of oxygen in musculoskeletal system growth and development.

Dr. Samuel joined the Hampton University faculty on July 1, 2011 as the Assistant Dean of the School of Engineering & Technology (SET) and an Associate Professor in the Department of Chemical Engineering. He is actively involved in the growth of the SET’s enrollment and curriculum expansion into areas such as computer engineering and biological engineering. He is rapidly establishing an interdisciplinary biomedical research team at Hampton University involving undergraduate and graduate students and faculty members from the Schools of Science, the School of Engineering & Technology, and the health-related schools (nursing, pharmacy and physical therapy). Dr. Samuel’s ultimate goal is to develop a biological engineering undergraduate and graduate degree-granting program intimately woven to the parallel development of a cutting-edge Hampton University-based biological engineering research faculty, as has been previously modeled in exceedingly successful degree programs of Hampton University’s Department of Physics.

Areas of Research:

  1. Polyelectrolyte multilayer thin film coatings
  2. Osteoconductive surface coatings
  3. Non-viral gene delivery systems
  4. Implant-bone tissue integration
  5. Influence of hypoxia on bone growth
  6. Adenosine receptor signaling in chronic adaptation of osteoblast to hypoxia

Selected Recent Publications

  1. Moskowitz JS, Blaisse MR, Samuel RE, Hsu HP, Harris MB, Martin SD, Lee JC, Spector M, Hammond PT. The effectiveness of the controlled release of gentamicin from polyelectrolyte multilayers in the treatment of Staphylococcus aureus infection in a rabbit bone model. Biomaterials. 2010 31: 6019-6030.
  2. DeMuth PC, Su X, Samuel RE, Hammond PT, Irvine DJ. Nano-layered microneedles for transcutaneous delivery pf polymer nanoparticles and plasmid DNA. Advanced Materials 2010. 22943)4851-4856.
  3. Macdonald ML, Samuel RE, Shah NJ, Beben YM, Padera R, Hammond PT. Biologic-Eluting Surfaces Enhance Implant-Tissue Interactions. Biomaterials. 2010 31: 6019-6030.
  4. Shah NJ, Macdonald ML, Beben YM, Padera R, Samuel RE, Hammond PT. Tunable dual growth factor delivery from polyelectrolyte multilayers films. Biomaterials 2011 32(26): 6183-93.
  5. Samuel RE, Shukla A, Wang MX, Paik DH, Fang JC, Schmidt DJ, Hammond PT. Osteoconductive protamine-based polyelectrolyte multilayer functionalized surfaces. Biomaterials 2011 32(30):7491-502.